Ipamorelin
Characteristics
| Molecular Formula | C38H49N9O5 |
| CAS-number | 170851-70-4 |
| Molar Mass | 711.85 g/mol |
| Chemical Formula | H-Aib-His-D-2-Nal-D-Phe-Lys-NH2 |
| Amino Acid Sequence | Aib-His-D-2-Nal-D-Phe-Lys |
| Synonyms | NNC 26-0161, Ipamorelin acetate |
| Solubility | Water-soluble |
| Organoleptic Profile | White to off-white powder |
| Composition | Lyophilized powder – requires reconstitution |
| Form | Lyophilized powder |
| Storage | Store at -20 °C, dry and protected from light. Short-term storage at 2-8 °C is acceptable for up to 4 weeks. |
How does Ipamorelin work?
Ipamorelin is a selective agonist of the ghrelin receptor (GHS-R1a) and stimulates the release of growth hormone (GH) from the anterior pituitary gland. Unlike other GH secretagogues, Ipamorelin does not significantly increase levels of adrenocorticotropic hormone (ACTH), cortisol, or prolactin. This selectivity makes Ipamorelin a promising research peptide for studying the effects of GH secretion without the confounding effects of other hormones.
Ipamorelin binds to the GHS-R1a receptor, which is primarily expressed in the hypothalamus and pituitary gland. Upon binding, it triggers a cascade of signaling events that ultimately lead to the synthesis and secretion of GH. The released GH then binds to its receptors in various target tissues, such as the liver, muscle, and bone, to exert its anabolic effects.
Handling & Safety
Handle as a laboratory research chemical of unknown hazard. Use gloves and eye protection, avoid inhalation of the lyophilized powder, and follow standard laboratory handling procedures.
Reconstitute and store according to the product label. Lyophilized material should be kept cool, dry and protected from light; reconstituted material should be held at 2-8°C and protected from light.
The safety profile of Ipamorelin has not been established. This compound is supplied for laboratory research use only and is not approved for human or veterinary use.
Summary
Ipamorelin is a research peptide and selective ghrelin receptor agonist that stimulates the secretion of growth hormone (GH) from the pituitary gland. Animal studies have measured GH release and its selectivity relative to cortisol and prolactin. Ipamorelin’s selectivity for GH secretion without significantly affecting other hormones makes it a promising research tool in the fields of endocrinology, metabolism, and aging. However, further research is needed to fully elucidate its mechanisms of action, potential research applications, and safety profile in mammalian models.
Resource
Supplied by Power Peptides within the Research Peptides category alongside related reference materials including NAD+, GLP-1SM Research Compound, and Research Atomizer Add-on System. All products on this site are intended for research and development purposes only and are not meant for human consumption of any kind. The statements made within this website have not been evaluated by the U.S. Food and Drug Administration (FDA). Neither the statements nor the products offered by this company are intended to diagnose, treat, cure, or prevent any disease.
