Selank
Characteristics
| Molecular Formula | C33H57N11O9 |
| CASNumber | 129954-34-3 |
| Molar Mass | 751.89 g/mol |
| Amino Acid Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| Synonyms | TP-7, Immunomodulator Selank, Antidepressant Selank, Selanc |
| Solubility | Water-soluble |
| Organoleptic Profile | White to off-white powder |
| Composition | Lyophilized powder – requires reconstitution |
| Form | Lyophilized powder |
| Storage | Store at -20 °C, dry and protected from light. Short-term storage at 2-8 °C is acceptable for up to 4 weeks. |
How is Selank Used in Research?
Selank exerts its effects through multiple mechanisms of action. It has been shown to modulate the expression of brain-derived neurotrophic factor (BDNF) and its receptor TrkB, which are crucial for neuronal survival, growth, and synaptic plasticity. Selank also interacts with the GABAergic system, enhancing the inhibitory neurotransmission and modulating neurotransmitter signaling. Additionally, Selank has been found to regulate the activity of serotonin and dopamine, neurotransmitters involved in mood regulation and cognitive function.Furthermore, Selank exhibits immunomodulatory and anti-inflammatory properties. Studies have examined its interaction with cytokine signalling (IL-6, TNF-alpha) and natural killer cells. Selank has also been examined for antioxidant effects in models of oxidative stress-induced cell damage. These mechanisms reflect what Selank peptide does in research. Study protocols varied across experimental models.
Summary
Selank is a synthetic peptide that has been widely studied for its involvement in neurobiological and immune-related pathways. Its activity has been explored in relation to stress response, mood-associated processes, cognitive function, and neuronal signaling, as well as interactions with immune system pathways. While existing findings provide insight into its biological activity, further investigation is required to better characterize its mechanisms and effects across different experimental models. As a research compound, Selank continues to be of interest in the study of complex neurological and biochemical systems.
Resource
Supplied by Power Peptides within the Research Peptides category alongside related reference materials including CJC-1295 (no DAC), Oxytocin Research Atomizer System, and Semax. All products on this site are intended for research and development purposes only and are not meant for human consumption of any kind. The statements made within this website have not been evaluated by the U.S. Food and Drug Administration (FDA). Neither the statements nor the products offered by this company are intended to diagnose, treat, cure, or prevent any disease.
