VIP
Characteristics
| Molecular Formula | C147H238N44O42S |
| CAS | 40077-57-4 |
| Molar Mass | 3325.8 g/mol |
| Amino Acid Sequence | His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn |
| Synonyms | VIP, Vasoactive Intestinal Polypeptide, PHM27 |
| Solubility | Soluble in Water |
| Organoleptic Profile | White powder |
| Composition | Lyophilized powder – requires reconstitution |
| Form | Lyophilized powder |
| Storage | Store at -20 °C, dry and protected from light. Short-term storage at 2-8 °C is acceptable for up to 4 weeks. |
How is VIP studied?
Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide that has been explored in preclinical laboratory research for its interaction with G protein-coupled receptors such as VPAC1 and VPAC2. These receptors are expressed in various mammalian tissues, including the brain, intestines, and immune-related cells. In mammalian research models, VIP peptide has been observed to activate signaling pathways, including those involving cyclic AMP (cAMP), which play a role in cellular communication. These studies have explored VIP’s role in smooth muscle biology, glandular secretion, and immune cell signaling under controlled laboratory conditions. The research continues to advance understanding of complex cellular response mechanisms but does not provide conclusions regarding VIP peptide safety or effects in humans.
Research Focus
Vasoactive Intestinal Peptide (VIP) has been studied in preclinical laboratory models for its role in several biological systems. In these research environments, VIP has been explored for its potential influence on:
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Cell signaling pathways associated with inflammation
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Neural cell communication and protection mechanisms under oxidative stress conditions
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Immune response modulation, including signaling interactions involving T cell subsets
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Smooth muscle behavior and vascular signaling
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Respiratory and gastrointestinal cell models examining glandular and barrier function
Preclinical Observations
In preclinical laboratory studies, Vasoactive Intestinal Peptide (VIP) peptide has been investigated for its effects on biological systems such as vascular tone and gastrointestinal secretion. Preclinical studies have examined its activity in vascular, smooth-muscle and glandular models. It is important to note that VIP has not been evaluated or approved for human use, and its effects in humans are not established.
Summary
Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide that has been studied in preclinical laboratory settings for its role in various biological systems. Research in mammalian models has examined VIP’s interaction with pathways involved in vascular tone, smooth muscle behavior, immune response, and cellular signaling. These investigations support its relevance in advancing understanding of neuroendocrine and immunological functions. However, VIP is not approved for human or veterinary use, and no definitive conclusions can be drawn about its safety or efficacy outside of experimental settings.
Resource
Supplied by Power Peptides within the Research Peptides category alongside related reference materials including PP-CAG Research Compound, Thymalin, and BPC-157 10mg + TB-500 10mg + GHK-Cu 50mg (70mg blend). All products on this site are intended for research and development purposes only and are not meant for human consumption of any kind. The statements made within this website have not been evaluated by the U.S. Food and Drug Administration (FDA). Neither the statements nor the products offered by this company are intended to diagnose, treat, cure, or prevent any disease.





